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MN 553 Unit 9 DQ 1

Unit 9: Unit 9: Complementary and Alternative Medicine (CAMs) and Pharmacogenomics – Discussion 
To access the Discussion Board, click this unit’s Discussion link, on the left. Be sure to post a response to all Discussion topics.
Topic: Pharmacogenomics in Primary Care
Explain one of the following statements in your own words. Give an example of implications for you as the prescribing primary care provider.

  1. Carbamazepine has a black box warning recommending      testing for the HLA-B*1502 allele in patients with Asian ancestry prior to      starting therapy.
  2. Testing for CYP2D6 variants prior to starting tamoxifen      for breast cancer.
  3. A genetic variation in how the metabolite of the cancer      drug irinotecan SN-38 is inactivated by the body.

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